CMYK - Working Space
Making your choice of CMYK working space isn't that different
to RGB except of the list of available colour profiles are rather
different. Again, having "Advanced Mode" activated gives us a more
extensive list. Since desktop inkjet printers from Epson, Canon and HP
actually require RGB data rather than CMYK and so configuring this
particular working space will have little or no influence in their actual
workflow.

As mentioned above, the choice for you make is pretty much irrelevant
if using a consumer class inkjet printer. In my case I just picked US.
Web Coated (SWOP) V2. We can also have pick the old Photoshop 4
or 5 default CMYK options, the ColorSync settings (Mac only), or even
customise our own settings.
Greyscale - Working Space
With the Greyscale working space we have access to two gamma
settings, a series of five pre-set dot gain curves, the ColorSync "Grey
Work Space" (Mac only) and the ability to customise the dot gain to
our own requirements. This latter option is of particular significance to
users of
Jon Cones
Piezography Black and White printing system (discussed in a
separate essay). The screenshots below show the various options and a
typical customised "Dot Gain" curve.

Please note that if you choose to use a "Custom Gamma" or "Dot
Gain" this will be the working space listed in the Grey working space
pop-up menu.

A very important point regarding Greyscale is that it is not
tied to the CMYK setup! This is why some legacy greyscale documents might
not look quite the same as they did in Photoshop 5.x
Spot - Working Space
The Spot pop-up menu is broadly similar to the greyscale. The
options that we find include a series of five pre-set "dot gain"
options and the facility for customising the "dot gain" curve if
required. In my case I simply selected the standard 20% option.